February 17, 2020

Phthalates Associated with Obesity and Substance Abuse in Humans

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Phthalates, a chemical class used in the manufacture of plastic fiber and is associated with reproductive health issues, has been associated with increased fetal and insulin resistance in adult males. The study, published recently in an online publication of the journal Environmental and Environmental Health, was conducted by the University of Rochester Medical Center.

The study adds to the growing body of evidence linking phthalates to human health problems. Previous scientific studies have examined the association between phthalates and poor water quality in adolescents with subtle changes in the reproduction of male offspring. It is this connection between phthalates and testosterone that has helped to establish a solid foundation for the University of Rochester study, according to Dr Richard Stahlhut, lead author.

"Significant declines in testosterone levels and oral quality have been observed in the United States and other countries over the last decade, which calls for clarification," Stahlhut said. "While we may not claim that phthalates are a major cause, I do know that there is a list of substances that require careful consideration."

The research group emphasized that because low levels of testosterone can increase the risk of stomach fat and premature diabetes, phthalates are often linked to obesity.

They analyzed urine, blood pressure and other data from the National Health and Nutrition Examination Survey (NHANES), a large, multi-ethnic, cross-section of Americans. Data is collected by the Institutions for Control and Prevention.

Researchers have been examining data from 199 to 2002, in recent years when the numbers for phthalates are available. The NHANES studied phthalate exposure data for 1,451 patients, including geese and ginger. For 651 subjects in the study, data were collected on fasting glucose and insulin levels, which are used to calculate insulin resistance.

According to the study, more than 75 percent of the U.S. population phthalates contain large quantities in their urine. "Unfortunately, there is still a lot to learn about phthalates," Stahlhut said. "The difficult problem is that only small-scale chemical events can contribute to these problems."

Consumer reaction and product regulation stems from research such as providing product and food manufacturers to find new ways.

Phthalates are commonly used as soft and plastic for products made with polyvinyl chloride (PVC), such as plastics, which are used in a variety of consumer and personal care products including pharmaceuticals. food, sports, and medicine / drug paraphernalia The most commonly used phthalate is DEHP. The contamination of foods derived from plastic food products from PVC was treated with phthalates.

Phthalates are also used in the manufacture of pharmaceuticals, cotton, soap, oils, oils, paints, table towels, and pesticides. A type of phthalate used in cosmetics and perfumes, shampoos, make-up, seasonings and hair.

In Europe, products containing phthalate substances at all times during the period in 2005 were six phthalate soft substances used in PVC toys and child care products that were referred to children their mouths.

The Food and Drug Administration does not have a role to play in regulating the use of phthalates despite calls from some consumer advocates. California is the first state to attempt to regulate the products contained in this chemical. However, legislation to prevent phthalate substances from children's toys, leather equipment, and other products of child protection was repealed by the California Convention.